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A study confirms that galantamine stimulates lucid dreaming

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Ashiren
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A study confirms that galantamine stimulates lucid dreaming
PostPosted: Tue 09 Oct, 2018  Reply with quote

Pre-sleep treatment with galantamine stimulates lucid dreaming: A double-blind, placebo-controlled, crossover study.

Quote:
Abstract
Lucid dreaming is a remarkable state of consciousness in which one is aware of the fact that one is dreaming while continuing to dream. Based on the strong relationship between physiological activation during rapid eye-movement sleep and lucid dreaming, our pilot research investigated whether enhancing cortical activation via acetylcholinesterease inhibition (AChEI) would increase the frequency of lucid dreams and found AChEI to be a promising method for lucid dream induction. In the current study we sought to quantify the size and reliability of the effect of AChEI on lucid dreaming, dream recall and dream content as well as to test the effectiveness of an integrated lucid dream induction protocol which combined cholinergic stimulation with other methods for lucid dream induction. Participants (N = 121) with high dream recall and an interest in lucid dreaming were randomly assigned counterbalanced orders of 3 doses of galantamine (0, 4 and 8 mg). On 3 consecutive nights, they awoke approximately 4.5 hours after lights out, recalled a dream, ingested the capsules and stayed out of bed for at least 30 minutes. Participants then returned to bed and practiced the Mnemonic Induction of Lucid Dreams technique while returning to sleep. The percentage of participants who reported a lucid dream was significantly increased for both 4 mg (27%, odds ratio = 2.29) and 8 mg doses (42%, odds ratio = 4.46) compared to the active placebo procedure (14%). Galantamine also significantly increased dream recall, sensory vividness and complexity (p<0.05). Dream recall, cognitive clarity, control, positive emotion, vividness and self-reflection were increased during lucid compared to non-lucid dreams (p<0.0001). These results show that galantamine increases the frequency of lucid dreams in a dose-related manner. Furthermore, the integrated method of taking galantamine in the last third of the night with at least 30 minutes of sleep interruption and with an appropriately focused mental set is one of the most effective methods for inducing lucid dreams available today.


https://www.ncbi.nlm.nih.gov/pubmed/30089135, and yes, the one of authors is Stephen LaBerge.

They used WBTB (4.5h + 0.5h) and MILD technique, the galantamine (or placebo) was taken during the wake phase. Galantamine group reports more lucid dreams and general more dream recall. This is the first(?) double-blind controlled study which confirms galantamine works for inducing lucid dreams, not only yet another anectodal evidence.


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Obliverum
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PostPosted: Wed 10 Oct, 2018  Reply with quote

thanks for sharing this! ive seen lots of good studies on galantamine but a double-blind study is great.

ive tried it a few times and the one time i managed to get back to sleep i did have lucid dreams... but i cant afford the lost sleep so i gave up on it. I have pretty high chances of having a lucid dream if I do the preparation and a solid WBTB+MILD without any drugs, but i have a 0% chance of having a lucid dream if i cant sleep eek2

it would be interesting to see a study on the effects on a more average population of dreamers. i imagine folks who go to lucid dreaming retreats are much more likely to be skilled lucid dreamers already, and WBTB+MILD is already very effective, so just a little extra kick can get them over the edge to lucidity more easily than with any random person.



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